CVE-2026-100845

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

CVSS v3 7.8 HIGH

7.8^/10

CVSS v3 : HIGH

Vector :

Exploitability : 1.8 / Impact : 5.9

Attack Vector LOCAL

Attack Complexity LOW

Privileges Required NONE

User Interaction REQUIRED

Confidentiality Impact HIGH

Integrity Impact HIGH

Availability Impact HIGH

Scope UNCHANGED

References

Link	Resource
https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr	Exploit Vendor Advisory
https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-numpyreader	Third Party Advisory
https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr	Exploit Vendor Advisory

Configurations

Configuration 1 (hide)

cpe:2.3:a:project-monai:monai:*:*:*:*:*:*:*:*

History

30 Sep 2026, 15:25

Type	Values Removed	Values Added
First Time		Project-monai monai Project-monai
CPE		cpe:2.3:a:project-monai:monai::::::::
References	~~() https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr -~~	() https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr - Exploit, Vendor Advisory
References	~~() https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-numpyreader -~~	() https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-numpyreader - Third Party Advisory

28 Sep 2026, 14:17

Type	Values Removed	Values Added
References	~~() https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr -~~	() https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr -

27 Sep 2026, 02:17

Type	Values Removed	Values Added
New CVE

Information

Published : 2026-09-27 02:17

Updated : 2026-09-30 15:25

NVD link : CVE-2026-100845

Mitre link : CVE-2026-100845

CVE.ORG link : CVE-2026-100845

JSON object : View

Products Affected

project-monai

monai

CWE

CWE-502

Deserialization of Untrusted Data

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